Description: Germ-line and somatic mutations are recognized as significant causes of human disease, and so the detection, identification, and study of mutagens in the environment are of increasing interest. Environmental Mutagenesis describes our current knowledge of the molecular mechanisms of mutagenesis and assesses the role of mutagens in cancer and inherited disease. Full details are also provided for all the major in vivo and in vitro methods of mutagenicity testing, including recently developed methods such as fluorescence in situ hybridization (FISH), the use of genetically engineered cells, and transgene technology. This book presents a unique overview of the current status of mutagenicity research and genetics toxicology in the form of reviews by leading researchers in the field. It is essential reading for all with an interest in genetic toxicology and molecular carcinogenesis, including molecular geneticists, genetic counselors, and clinicians.

Please Wait